standard-title PNNR

PNNR

Avviso pubblico PNRR 2023
Sono stati approvati n. 6 progetti con l’Istituto come Destinatario Istituzionale.

Codice Locale Progetto

Titolo

DI

PNRR-POC-2023-12377318

Radiolabeled FPR1 Inhibitors for a Theranostic Application on Solid TumorsRITAST

Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT2-2023-12377998 ValproIc acid to potentiate anti-EGFR treatment efficacy and prevent/revert resistance In colorectal cancer (VICTORIA) Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT2-2023-12377462

Clinically approved drugs targeting pyruvate kinase M2: a drug repurposing pathway to move forward the treatment of glioblastoma

Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT2-2023-12377323

A multimodal and multicenter approach for biobanking of biological materials and associated clinical data to improve rehabilitation in breast cancer patients with cognitive impairment

Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT2-2023-12377133 Extended genomic profiling of circulating tumor DNA (ctDNA) to improve precision treatment of metastatic colorectal cancer patients Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT1-2023-12378005 Spatial radiomIcs and tRanscriptomics to the dIscovery of the cross-link between colon cancer and chrOnic kidney disease in the SIRIO study Istituto nazionale tumori Fondazione Giovanni Pascale
     

Inoltre, n. 22 progetti sono stati approvati con l’Istituto come unità esterna partecipante.

 

Codice Locale Progetto       Titolo DI
PNRR-TR1-2023-12377450 DECODING THE EXTRACELLULAR VESICLES-DRIVEN COMMUNICATION IN THE MICROENVIRONMENT OF HAIRY CELL LEUKEMIA TO IMPROVE PATIENT CARE MANAGEMENT Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-TR1-2023-12377199 New preclinical and clinical approaches to mesothelioma, an archetypal inflammatory tumor Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT2-2023-12377496 Targeting therapy-induced paracrine signaling pathways in prostate cancer to prevent disease progression and resistance Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT2-2023-12377229 New theranostic biomarkers of Intraductal papilary mucinous neoplasm (IPMN) progression to pancreatic cancer for patients’ outcome improvement Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-POC-2023-12378165 A PROOF OF CONCEPT CLINICAL TRIAL OF COMBINATION OF IMMUNE CHECKPOINT INHIBITION AND MICROBIOTA-DERIVED POSTBIOTIC IN TRIPLE NEGATIVE BREAST CANCER PATIENTS Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-POC-2023-12377326 Identification of targetable vulnerabilities in redox homeostasis pathways as a novel therapeutic approach for human T-cell malignancies Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-TR1-2023-12377102 MultiomIc aNalysis to Develop a predictive Signature plEural mesoThelioma-MINDSET Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT2-2023-12377164 Characterization of immune genotypes and antibody profiles to foster the discoVERY of diagnostic bioMARKERS of liver cancer development (VERYMARKERS) Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT2-2023-2378166 Preventive and prEdictive diagNostiC approaches in High-risk meLanoma: implications for hereditability and response to therapy. The PENCIL project Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-POC-2023-12377841 Scale-up the industrial development of CD99-null exTracellular vesicles (EVs) As theRapeutic Tools by using Ewing sarcoma as prototype (START) Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-TR1-2023-12378226 Soft Tissue Sarcoma: instrumented evaluation of motor performance and impact of Robotic Rehabilitation,  Nutrition and efficacy of Nutraceuticals, and Quality of Life assessment (START-RUN) Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-TR1-2023-12377644 PROFILES OF INTRATUMORAL MICROBIOTA IN NEUROENDOCRINE NEOPLASMS AND SOFT  TISSUE SARCOMAS: NEW PERSPECTIVES FOR DIAGNOSIS, PROGNOSIS AND PREDICTION OF  TREATMENT EFFICACY IN RARE TUMORS Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-POC-2023-12378113 A composite assay for HER2-positive early-stage breast cancer management Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-POC-2023-12377696 Innovative drug delivery nanophotonic platform for implementation of sarcomas therapy (DEEPLY) Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT2-2023-12377469 Microbiota: its role in chronic inflammation, IBD and risk of colorectal cancer. Evaluation of a predictive  prognostic model with therapeutic implications. Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT2-2023-12378239 Radio-immunotherapy of solid tumors Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-TR1-2023-12377022 Does prehabilitation be able to favorably impact on the pathway of head and neck cancer patients, candidate to surgery or chemoradiotherapy as primary treatment? A prospective clinical trial Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT2-2023-12378361 Biomarker identification to guide therapeutic strategy in locally advanced rectal cancer Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-TR1-2023-12377293 Rare breast cancer subtypes: towards a better understanding of the biology to improve clinical management Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT2-2023-12377570 Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation after robot-assisted surgical treatment of genitourinary cancers Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-TR1-2023-12378400 UNDERSTANDING THE RAREST GYNECOLOGICAL CANCERS: A MULTI -OMICS PLATFORM FOR IMPROVED PATIENTS MANAGEMENT (ROAR) Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MCNT2-2023-12377963 KEAPness: a transcriptional framework for the molecular diagnosis of immunotherapy response in lung cancer with a tumor-agnostic potential Istituto nazionale tumori Fondazione Giovanni Pascale

Avviso pubblico PNRR 2022
Sono stati approvati n. 4 progetti con l’Istituto come Destinatario Istituzionale.

Codice Locale Progetto

Titolo

DI

PNRR-MAD-2022-12376670

PREcision therapeutic STrategies for the treatment of colorectal and hepatOcellular cancer (PRESTO)

Istituto nazionale tumori Fondazione Giovanni Pascale

PNRR-MAD-2022-12376570

Identification of common pathogenic mechanisms driving squamous cell carcinomas of the anogenital tract and head&neck region to develop overarching therapeutic strategies

Istituto nazionale tumori Fondazione Giovanni Pascale

PNRR-POC-2022-12376329

From diagnostic to theranostic CXCR4-targeting PET probe. Proof of concept in Non Small Cell Lung Cancer (NSCLC)-PDX model

Istituto nazionale tumori Fondazione Giovanni Pascale

PNRR-POC-2022-12375769

MOLECULAR MIMICRY TO IMPROVE LIVER CANCER IMMUNOTHERAPY

Istituto nazionale tumori Fondazione Giovanni Pascale

Inoltre, n. 8 progetti sono stati approvati con l’Istituto come unità esterna partecipante

Codice Locale Progetto

Titolo

DI

PNRR-MAD-2022-12376756 Singlecelldissectionofthe
tumormicroenvironmentinbladdercancerfortheidentificationofpredictivetoolsandnewtherapies

Istituto nazionale tumori Fondazione Giovanni Pascale

PNRR-MAD-2022-12375663

OvercomingPARPiresistanceinovariancancer:frombiologytoclinicalapplication

Istituto nazionale tumori Fondazione Giovanni Pascale

PNRR-MAD-2022-12375670

Addressingliverfibrosispreventionandtreatment:anunbiasedqueryonthehepaticmicroenvironmentwith
aperspectivetargetingofthepro-fibrotickinaseHIPK2

Istituto nazionale tumori Fondazione Giovanni Pascale

PNRR-MAD-2022-12376707

Decipheringthebiologyofrelapsed/refractorydiffuselargeBcelllymphoma(R/RDLBCL)subtypes:
IdentificationofpredictivebiomarkersincludingmiRNA-basedtumorsignaturestooptimizesequential
treatmentdecisionstowardstheeffectiveimprovementofpatientlong-termsurvival

Istituto nazionale tumori Fondazione Giovanni Pascale

PNRR-POC-2022-12375713 TArgetingdrugresistantmelanomawithmiCroRNAs
deliveredbyLipidNanoparTICles(TACTIC)
Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-POC-2022-12376579 Engineeredlisyloxidaselipid-basednanovesiclesforthetreatmentofsolidtumors:onthepathtoclinical
applicationTRUST
Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MAD- 2022-12376767 MITOCHONDRIAL GENETIC AND FUNCTIONAL ANALYSIS FOR A PERSONALIZED FRAILTY ASSESSMENT IN CRITICALLY ILL PATIENTS (MITOFRAILTY) Istituto nazionale tumori Fondazione Giovanni Pascale
PNRR-MAD-2022-12376567 “Low Dose Tamoxifen and Lifestyle Changes for Breast Cancer Prevention: a randomized phase II biomarker trial in subjects at increased risk Istituto nazionale tumori Fondazione Giovanni Pascale