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Long-term memory T cells as preventive anticancer immunity elicited by TuA-derived heteroclitic peptides.Mauriello A, Cavalluzzo B, Manolio C, Ragone C, Luciano A, Barbieri A, Tornesello ML, Buonaguro FM, Tagliamonte M, Buonaguro L.J Transl Med. 2021 Dec 24;19(1):526. doi: 10.1186/s12967-021-03194-6.PMID: 34952611
Imaging-guided radiofrequency ablation of osteoid osteoma in typical and atypical sites: Long term follow up.Somma F, Stoia V, D’Angelo R, Fiore F.PLoS One. 2021 Mar 18;16(3):e0248589. doi: 10.1371/journal.pone.0248589. eCollection 2021.PMID: 33735214
Aberrant Expression of Long Non Coding RNA HOTAIR and De-Regulation of the Paralogous 13 HOX Genes Are Strongly Associated with Aggressive Behavior of Gastro-Entero-Pancreatic Neuroendocrine Tumors.Di Mauro A, Scognamiglio G, Aquino G, Cerrone M, Liguori G, Clemente O, Di Bonito M, Cantile M, Botti G, Tafuto S, Tatangelo F.Int J Mol Sci. 2021 Jun 30;22(13):7049. doi: 10.3390/ijms22137049.PMID: 34208964
Prognostic and Predictive Role of CXC Chemokine Receptor 4 in Metastatic Colorectal Cancer Patients.Ottaiano A, Scala S, Normanno N, Botti G, Tatangelo F, Di Mauro A, Capozzi M, Facchini S, Tafuto S, Nasti G.Appl Immunohistochem Mol Morphol. 2020 Nov/Dec;28(10):755-760. doi: 10.1097/PAI.0000000000000828.PMID: 31985548
β2-AR blockade potentiates MEK1/2 inhibitor effect on HNSCC by regulating the Nrf2-mediated defense mechanism.Mele L, Del Vecchio V, Marampon F, Regad T, Wagner S, Mosca L, Bimonte S, Giudice A, Liccardo D, Prisco C, Schwerdtfeger M, La Noce M, Tirino V, Caraglia M, Papaccio G, Desiderio V, Barbieri A.Cell Death Dis. 2020 Oct 13;11(10):850. doi: 10.1038/s41419-020-03056-x.PMID: 33051434
Valproic Acid Synergizes With Cisplatin and Cetuximab in vitro and in vivo in Head and Neck Cancer by Targeting the Mechanisms of Resistance.Federica Iannelli; Andrea Ilaria Zotti; Maria Serena Roca; Laura Grumetti; Rita Lombardi; Tania Moccia; Carlo Vitagliano; Maria Rita Milone; Chiara Ciardiello; Francesca Bruzzese; Alessandra Leone; Ernesta Cavalcanti; Rossella De Cecio; Giuseppina Iachetta; Salvatore Valiante; Franco Ionna; Francesco Caponigro; Elena Di Gennaro; Alfredo Budillon. Frontiers in Cell and Developmental Biology 2020 Jul;8:732 DOI: 10.3389/fcell.2020.00732. Pmid: 33015030
Targeted sequencing analysis of cell-free DNA from metastatic non-small-cell lung cancer patients: clinical and biological implications.Pasquale R, Forgione L, Roma C, Fenizia F, Bergantino F, Rachiglio AM, De Luca A, Gallo M, Maiello MR, Palumbo G, Morabito A, Azzaro R, Normanno N.Transl Lung Cancer Res. 2020 Feb;9(1):61-70. doi: 10.21037/tlcr.2020.01.01.PMID: 32206554
Synergistic antitumor interaction of valproic acid and simvastatin sensitizes prostate cancer to docetaxel by targeting CSCs compartment via YAP inhibition.Iannelli F, Roca MS, Lombardi R, Ciardiello C, Grumetti L, De Rienzo S, Moccia T, Vitagliano C, Sorice A, Costantini S, Milone MR, Pucci B, Leone A, Di Gennaro E, Mancini R, Ciliberto G, Bruzzese F, Budillon A.J Exp Clin Cancer Res. 2020 Oct 8;39(1):213. doi: 10.1186/s13046-020-01723-7.PMID: 33032653
SARS-CoV-2 infection: NLRP3 inflammasome as plausible target to prevent cardiopulmonary complications?Quagliariello V, Bonelli A, Caronna A, Lombari MC, Conforti G, Libutti M, Iaffaioli RV, Berretta M, Botti G, Maurea N.Eur Rev Med Pharmacol Sci. 2020 Sep;24(17):9169-9171. doi: 10.26355/eurrev_202009_22867.PMID: 32965010
P53-regulated miR-320a targets PDL1 and is downregulated in malignant mesothelioma.Costa C, Indovina P, Mattioli E, Forte IM, Iannuzzi CA, Luzzi L, Bellan C, De Summa S, Bucci E, Di Marzo D, De Feo M, Mutti L, Pentimalli F, Giordano A.Cell Death Dis. 2020 Sep 14;11(9):748. doi: 10.1038/s41419-020-02940-w.PMID: 32929059
NLRP3 as Putative Marker of Ipilimumab-Induced Cardiotoxicity in the Presence of Hyperglycemia in Estrogen-Responsive and Triple-Negative Breast Cancer Cells.Quagliariello V, De Laurentiis M, Cocco S, Rea G, Bonelli A, Caronna A, Lombari MC, Conforti G, Berretta M, Botti G, Maurea N.Int J Mol Sci. 2020 Oct 21;21(20):7802. doi: 10.3390/ijms21207802.PMID: 33096896
New Deployable Expandable Electrodes in the Electroporation Treatment in a Pig Model: A Feasibility and Usability Preliminary Study.Izzo F, Ionna F, Granata V, Albino V, Patrone R, Longo F, Guida A, Delrio P, Rega D, Scala D, Pezzuto R, Fusco R, Di Bernardo E, D’Alessio V, Grassi R, Contartese D, Palaia R.Cancers (Basel). 2020 Feb 23;12(2). pii: E515. doi: 10.3390/cancers12020515.PMID: 32102182
Nano-Encapsulation of Coenzyme Q10 in Secondary and Tertiary Nano-Emulsions for Enhanced Cardioprotection and Hepatoprotection in Human Cardiomyocytes and Hepatocytes During Exposure to Anthracyclines and Trastuzumab.Quagliariello V, Vecchione R, De Capua A, Lagreca E, Iaffaioli RV, Botti G, Netti PA, Maurea N.Int J Nanomedicine. 2020 Jul 9;15:4859-4876. doi: 10.2147/IJN.S245170. eCollection 2020.PMID: 3276492
Major and ancillary features according to LI-RADS in the assessment of combined hepatocellular-cholangiocarcinoma.Granata V, Fusco R, Venanzio Setola S, Sandomenico F, Luisa Barretta M, Belli A, Palaia R, Tatangelo F, Grassi R, Izzo F, Petrillo A.Radiol Oncol. 2020 May 28;54(2):149-158. doi: 10.2478/raon-2020-0029.PMID: 32463393
Magnetic resonance imaging in the assessment of pancreatic cancer with quantitative parameter extraction by means of dynamic contrast-enhanced magnetic resonance imaging, diffusion kurtosis imaging and intravoxel incoherent motion diffusion-weighted imaging.Granata V, Fusco R, Sansone M, Grassi R, Maio F, Palaia R, Tatangelo F, Botti G, Grimm R, Curley S, Avallone A, Izzo F, Petrillo A.Therap Adv Gastroenterol. 2020 May 21;13:1-14. doi: 10.1177/1756284819885052. eCollection 2020.PMID: 32499833
Intravoxel Incoherent Motion Model of Diffusion Weighted Imaging and Diffusion Kurtosis Imaging in Differentiating of Local Colorectal Cancer Recurrence from Scar/Fibrosis Tissue by Multivariate Logistic Regression Analysis. Roberta Fusco, Vincenza Granata, Mario Sansone, Robert Grimm, Paolo Delrio, Daniela Rega, Fabiana Tatangelo, Antonio Avallone, Nicola Raiano, Giuseppe Totaro, Vincenzo Cerciello, Biagio Pecori and Antonella Petrillo. Appl. Sci. 2020: 10;8609. doi:10.3390/app10238609
Genetic trajectory and immune microenvironment of lung-specific oligometastatic colorectal cancer.Ottaiano A, Circelli L, Lombardi A, Scala S, Martucci N, Galon J, Buonanno M, Scognamiglio G, Botti G, Hermitte F, Savarese G, D’Amore L, Tatangelo F, Di Mauro A, Liguori G, Trotta AM, Napolitano M, Capozzi M, Tafuto S, Perri F, La Rocca A, Caraglia M, Nasti G.Cell Death Dis. 2020 Apr 24;11(4):275. doi: 10.1038/s41419-020-2480-6.PMID: 32332709
Evolution of Mutational Landscape and Tumor Immune-Microenvironment in Liver Oligo-Metastatic Colorectal Cancer.Ottaiano A, Caraglia M, Di Mauro A, Botti G, Lombardi A, Galon J, Luce A, D’Amore L, Perri F, Santorsola M, Hermitte F, Savarese G, Tatangelo F, Granata V, Izzo F, Belli A, Scala S, Delrio P, Circelli L, Nasti G.Cancers (Basel). 2020 Oct 21;12(10):3073. doi: 10.3390/cancers12103073.PMID: 33096795
Evidences of CTLA-4 and PD-1 Blocking Agents-Induced Cardiotoxicity in Cellular and Preclinical Models.Quagliariello V, Passariello M, Rea D, Barbieri A, Iovine M, Bonelli A, Caronna A, Botti G, De Lorenzo C, Maurea N.J Pers Med. 2020 Oct 19;10(4):E179. doi: 10.3390/jpm10040179.PMID: 33086484
Evaluation of average glandular dose and investigation of the relationship with compressed breast thickness in dual energy contrast enhanced digital mammography and digital breast tomosynthesis.Fusco R, Raiano N, Raiano C, Maio F, Vallone P, Mattace Raso M, Setola SV, Granata V, Rubulotta MR, Barretta ML, Petrosino T, Petrillo A.Eur J Radiol. 2020 Mar 3;126:108912. doi: 10.1016/j.ejrad.2020.108912. [Epub ahead of print]PMID: 32151787
Digital breast tomosynthesis and contrast-enhanced dual-energy digital mammography alone and in combination compared to 2D digital synthetized mammography and MR imaging in breast cancer detection and classification.Petrillo A, Fusco R, Vallone P, Filice S, Granata V, Petrosino T, Rosaria Rubulotta M, Setola SV, Mattace Raso M, Maio F, Raiano C, Siani C, Di Bonito M, Botti G.Breast J. 2020 May;26(5):860-872. doi: 10.1111/tbj.13739. Epub 2019 Dec 30.PMID: 31886607
Diffusion-Weighted MRI and Diffusion Kurtosis Imaging to Detect RAS Mutation in Colorectal Liver Metastasis.Granata V, Fusco R, Risi C, Ottaiano A, Avallone A, De Stefano A, Grimm R, Grassi R, Brunese L, Izzo F, Petrillo A.Cancers (Basel). 2020 Aug 26;12(9):E2420. doi: 10.3390/cancers12092420.PMID: 32858990
Coronavirus disease 2019 (COVID-19) in Italy: features on chest computed tomography using a structured report system.Roberto G, Roberta F, Paola BM, Alessandro M, Gianluigi P, Fabrizio U, Antonella P, Vincenza G, Palmino S, Antonietta MM, Beatrice F, Alfonso R, Salvatore C.Sci Rep. 2020 Oct 14;10(1):17236. doi: 10.1038/s41598-020-73788-5.PMID: 33057039
Chest CT Computerized Aided Quantification of PNEUMONIA Lesions in COVID-19 Infection: A Comparison among Three Commercial Software.Grassi R, Cappabianca S, Urraro F, Feragalli B, Montanelli A, Patelli G, Granata V, Giacobbe G, Russo GM, Grillo A, De Lisio A, Paura C, Clemente A, Gagliardi G, Magliocchetti S, Cozzi D, Fusco R, Belfiore MP, Grassi R, Miele V.Int J Environ Res Public Health. 2020 Sep 22;17(18):E6914. doi: 10.3390/ijerph17186914.PMID: 32971756
Can Beta-2-Adrenergic Pathway Be a New Target to Combat SARS-CoV-2 Hyperinflammatory Syndrome?-Lessons Learned From Cancer.Barbieri A, Robinson N, Palma G, Maurea N, Desiderio V, Botti G.Front Immunol. 2020 Sep 30;11:588724. doi: 10.3389/fimmu.2020.588724. eCollection 2020.PMID: 33117402
Tackling hepatocellular carcinoma with individual or combinatorial immunotherapy approaches.Tagliamonte M, Mauriello A, Cavalluzzo B, Ragone C, Manolio C, Petrizzo A, Buonaguro L.Cancer Lett. 2020 Mar 31;473:25-32. doi: 10.1016/j.canlet.2019.12.029.PMID: 31875523
SARS-CoV-2 RNA polymerase as target for antiviral therapy.Buonaguro L, Tagliamonte M, Tornesello ML, Buonaguro FM.J Transl Med. 2020 May 5;18(1):185. doi: 10.1186/s12967-020-02355-3.PMID: 3237075
Prognostic and Predictive Role of CXC Chemokine Receptor 4 in Metastatic Colorectal Cancer Patients.Ottaiano A, Scala S, Normanno N, Botti G, Tatangelo F, Di Mauro A, Capozzi M, Facchini S, Tafuto S, Nasti G.Appl Immunohistochem Mol Morphol. 2020 Nov/Dec;28(10):755-760. doi: 10.1097/PAI.0000000000000828.PMID: 31985548
Study of Ras Mutations’ Prognostic Value in Metastatic Colorectal Cancer: STORIA Analysis.Ottaiano A, Normanno N, Facchini S, Cassata A, Nappi A, Romano C, Silvestro L, De Stefano A, Rachiglio AM, Roma C, Maiello MR, Scala S, Delrio P, Tatangelo F, Di Mauro A, Botti G, Avallone A, Nasti G.Cancers (Basel). 2020 Jul 16;12(7):E1919. doi: 10.3390/cancers12071919.PMID: 32708575
Multiplex immunohistochemistry assay to evaluate the melanoma tumor microenvironment.Scognamiglio G, Capone M, Mallardo D, Botti G, Ascierto PA, Madonna G.Methods Enzymol. 2020;635:21-31. doi: 10.1016/bs.mie.2019.07.045. Epub 2019 Aug 22.PMID: 32122547
Major and ancillary features according to LI-RADS in the assessment of combined hepatocellular-cholangiocarcinoma.Granata V, Fusco R, Venanzio Setola S, Sandomenico F, Luisa Barretta M, Belli A, Palaia R, Tatangelo F, Grassi R, Izzo F, Petrillo A.Radiol Oncol. 2020 May 28;54(2):149-158. doi: 10.2478/raon-2020-0029.PMID: 32463393